Was born in Damascus (Syria) in 1981, her family had a long history of political activism against the dictatorship in Syria since 1963 and moreover, since the start of the period of Father Assad in 1970, as her parents had met in this year during a protest.

Her father was detained, tortured, and disappeared around 9 times, so it was the motive for her to be a lawyer.

Since 2004, she became a lawyer and she used to defend political prisoners before the Supreme Security State Court,  she became a trainer on many topics related to human rights in 2007, the same year that she got a travel ban by the Syrian authority for her human rights activism, which lasted until 2014.

She was a member of the Arab Organization for Human Rights (Syria brunch), she did many studies on orphanages in Syria, sexual abuses against children, sexual abuses and exploitation against Iraqi Female refugees, Minors labor, and gender inequality.

With the start of the Syrian revolution in 2011, she dedicated her fight to defending and supporting political detainees and families of disappeared and missing and started to study and get many diplomas in international and domestic laws related to this field.

She met her late husband Bassel Khartabil Safadi, a prominent Palestinian Syrian activist and global programmer during a protest in Eastern Ghouta (country of Damascus) in April 2011, Bassel was detained on March 15^th, 2012, just two weeks before their wedding, he was disappeared for 9 months in unofficial detention centers and military Saidnaya jail, subjected to torture, hunger, and ill-treatment to be finally transferred to the Central Prison of Damascus, then they got married in prison on January 7^th 2013.

She was a co-founder of FREEEBASSEL Campaign, through this campaign, they could get the attention of the international community and push the international actors to put the file of detention, torture, exceptional courts, summary executions, and forcibly disappearance on the tables of all international forums, along with the efforts of other Syrian and international NGOs.

She spent 3 years visiting Bassel and hundreds of other male detainees in Adra prison 3 times a week, under bombing, clashes and weapons of snipers, providing all kinds of legal, emotional, personal and financial support to detainees and their families, struggling to make them heard and seen, she was one of the most essential resources for international actors and NGOs for accessing information to detention centers.

In 2015 Bassel was taken from Adra prison by a patrol of Military police to the Military field court, most of the governments were pushing the Syrian authorities to reveal his fate, hundreds of media reports were made, and hundreds of NGOs and activists were demanding his immediate release, then two years later in 2017, she announced about his execution by the military field court two day after his disappearance in 2015.

In 2018 Noura was forced to leave Syria to Lebanon, after many threats of being killed and many arrest warrants against her,  and she founded NoPhotoZone, a women-led and women target NGO that Bassel and Noura planned to do before Bassel’s detention.

NoPhotozone is a French non-profit and non-governmental organization founded in 2018 to provide legal support, psychological support, and advocacy for victims of detention, torture, forcibly disappearance, forcibly displaced, missing, and their families in Syria, Lebanon, and Turkey.

She was a co-founder of the Families for Freedom movement in 2016, which was the first family association in Syria.

She is a co-founder of the Voice Up Families Association in 2022.

She is a co-founder of Qarar Band.

As well as Noura is the author of the book Waiting 2015, and co-author of the book Syrian Law 2020, however, and she is the writer of many articles and studies.

She received many international recognitions, such as one of 8 Kick-ass Women in the World by Amnesty International – 2018, one of the most prominent 14 women human rights defenders in the world by Amnesty International -2019, Marianne Award by President Macron – 2022.

She got many titles on the Syrian level, such as the bride of the Syrian revolution, among the 100 faces of the Syrian revolution.